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Tiers range from Tier 1 (must have) to Tier 5 (Almost useless or useless).

There are 40 artifacts in total, each time you obtain you'll need more relics to obtain another. Relic cost will depend on artifact capacity.

Tier 1

Must Have All of these artifacts will help you in all aspects -- damage, gold, relic increment, and stage reduction.

Image Name Max Level Effect 1 (Increase per level) Effect 2 (Increase per level) All Damage (Increase per level) Corrosponding W1 Artifact Notes
Amulet of Storms Amulet of Storms 5 -100% Monsters Each Stage (-100%) None +600% All Damage (+300%) Worldly Illuminator Only the artifact which doesn't have effect 2.
Annihilation Orb Annihilation Orb Infinite +10% Gold Treasure Box Chance (+10%) +2% Gold Collection (+2%) +40% All Damage (+20%) Chest of Contentment + Future's Fortune Increases the amount of gold in a treasure chest.
Atomic wand Atomic Wand Infinite +2% Bonus Relic from Prestige (+2%) +5% Gold While Playing (+5%) +30% All Damage (+15%) Undead Aura + Crafter's Elixir None
Braid of Binding Braid of Binding Infinite

(125)

((250)

+5% Treasure Box Chance (+5%) +2% Gold Collection (+2%) +60% All Damage (+30%) Crown Egg + Future's Fortune Increases the chances of Chesterson Spawning. The default is 2%, 125 is 50% and 250 is 100%.
Circe's Mirror Circe's Mirror Infinite +2% Bonus Relic from Prestige (+2%) +30% Boss Gold (+30%) +30 All Damage (+15%) Undead Aura + Knight's Shield None
Cosmic Candle Cosmic Candle Infinite +2% DPS (+2%) +30% Boss Gold (+30%) +10% All Damage (+10%) Tincture of the Maker + Knight's Shield None
Horseshoe of Fortune Horseshoe of Fortune Infinite +1% Tap Damage (+1%) +10% Critical Damage (+10%) +60% All Damage (+30%) Drunken Hammer + Hero's Thrust None
Swift Swill Swift Swill Infinite +30% Boss Gold (+30%) +10% Gold Treasure Box Chance (+10%) +10% All Damage (+10%) Knight's Shield + Chest of Contentment Increases the Gold Dropped from Chesterson.

Tier 2

Should Have These are artifacts that give you damage, gold, and relic increment. However, their bonuses aren't as needed as tier 1 due to one of the artifact bonuses is not that useful enough to be in tier 1.

Image Name Max Level Effect 1 (Increase per level) Effect 2 (Increase per level) All Damage (Increase per level) Corrosponding W1 Artifact Notes
Anointment Ointment Anointment Ointment 25 -1% Upgrade Cost (-1%) +5% Gold While Playing (+5%) +300% All Damage (+150%) Ring of Wonderous Charm + Crafter's Elixir None
Azure Dragon Statuette Azure Dragon Statuette Infinite +5% Gold While Playing (+5%) +5% Arcane Channeling Duration (+5%) +40% All Damage (+20%) Crafter's Elixir + Axe of Resolution (Shadow Clone)
Inebriated Staff Inebriated Staff Infinite +2% Chance for 10x Gold (+2%) +2% Bonus Relic from Prestige (+2%) +30% All Damage (+15%) Divine Chalice + Undead Aura None
Mirror of Refraction Mirror of Refraction Infinite +1% Tap Damage (+1%) +0.25% Chance for 10x Gold (+0.25%) +60% All Damage (+30%) Drunken Hammer + Divine Chalice None
Morgana's Goblet Morgana's Goblet Infinite +2% Gold Collection (+2%) +30% Boss Gold (+30%) +60% All Damage (+30%) Future's Fortune + Knight's Shield None
Ring of Fire Ring of Fire Infinite +2% Gold Collection (+2%) +2% Critical Damage (+2%) +30% All Damage (+15%) Future's Fortune + Hero's Thrust None
Scarab of Insanity Scarab of Insanity Infinite +2% Bonus Relic from Prestige (+2%) +5% Monsters Gold (+5%) +30% All Damage (+15%) Undead Aura + Amulet of the Valrunes None
Scroll of Lightning Scroll of Lightning 25 +1% Critical Chance (+1%) +5% Monster Gold (+5%) +30% All Damage (+15%) Death Seeker + Amulet of the Valrunes None
Wand of Wonder Wand of Wonder 25 +5% Boss Time (+5%) +1% Critical Chance (+1%) +30% All Damage (+15%) Savior Shield + Death Seeker None

Tier 3

Ok to have If you have nothing else to salvage, you should keep them. Their bonuses aren't bad but not great either.

Image Name Max Level Effect 1 (Increase per level) Effect 2 (Increase per level) All Damage (Increase per level) Corrosponding W1 Artifact Notes
Chilling Chalice Chilling Chalice 25 -2% Arcane Channeling Cool Down (-2%) +5% Critical Damage (+5%) +400% All Damage (+200%) Barbarian's Mettle (Beserker Rage) + Hero's Thrust None
Demon Horns Demon Horns 25 -2% Inspiring Presence Cool Down (-2%) +5% Critical Damage (+5%) +400% All Damage (+200%) Hunter's Ointment + Hero's Thrust None
Mark of Dominance Mark of Dominance Infinite +2% DPS (+2%) +5% Chesterson Streak Duration (+5%) +10% All Damage (+5%) Tincture of the Maker + Ring of Opulance None
Merlin's Globe Merlin's Globe 25 -2% Summon Golem Cool Down (-2%) +5% Critical Damage (+5%) +400% All Damage (+200%) Ogre's Gauntlet (Shadow Clone) + Hero's Thrust None
Necklace of Nether Necklace of Nether 25 -2% Chesterson Streak Cool Down (-2%) +5% Critical Damage (+5%) +400% All Damage (+200%) Laborer's Pendent + Hero's Thrust None
Petals of Protection Petals of Protection 12 +1% Tap Damage (+1%) -2% Hero Death Chance (-2%) +260% All Damage (+130%) Drunken Hammer + Otherworldly Armor None
Ra's Ring Ra's Ring Infinite +.25% Chance for 10x Gold (+.25) +5% Gold While Playing (+5%) +30% All Damage (+15%) Divine Chalice + Crafter's Elixir None
Slippers of Sleep Slippers of Sleep 10 +2% DPS (+2%) -2% Revive Time (-2%) +10% All Damage (+5%) Tincture of the Maker + Warrior's Revival None
Mage's Mantle Mage's Mantle Infinite +40% Boss Gold (+40%) +5% Shadow Clone Duration (+5%) +60% All Damage (+30%) Knight's Shield + Ogre's Gauntlet None
Phoenix Renewed Phoenix Renewed Infinite +5% Summon Golem Duration (+5%) +2% Gold Collection (+2%) +70% All Damage (+35%) Ogre's Gauntlet + Future's Fortune None

Tier 4

Salvage if not needed These artifacts has one useful bonus but the other bonus downgrade them to be in tier 4.

Image Name Max Level Effect 1 (Increase per level) Effect 2 (Increase per level) All Damage (Increase per level) Corrosponding W1 Artifact Notes
Aphrodite's Baton Aphrodite's Baton 10 -2% Revive Time (-2%) +5% Gold While Playing (+5%) +70% All Damage (+35%) Warrior's Revival + Crafter's Elixir None
Boots of Wilting Boots of Wilting 25 -2% Heroic Burst Cool Down (-2%) +5% Critical Damage (+5%) +400% All Damage (+200%) Saintly Shield + Hero's Thrust None
Conjuror Crystal Conjuror Crystal 12 -2% Hero Death Chance (-2%) +10% Critical Damage (+10%) +230% All Damage (+115%) Otherworldly Armor + Hero's Thrust None
Elixir of Verve Elixir of Verve Infinite +5% Inspiring Presence Duration (+5%) +2% Gold Collection (+2%) +70% All Damage (+35%) Universal Fissure + Future's Fortune Currently bugged: Increases the duration of Arcane Channeling.
Magic Mist Magic Mist Infinite +5% Poisonous Touch Duration (+5%) +2% Gold Collection (+2%) +70% All Damage (+35%) Parchment of Importance + Future's Fortune None
Mercury's Earring Mercury's Earring Infinite +5% Critical Damage (+5%) +5% Inspiring Presence Duration (+5%) +30% All Damage (+15%) Hero's Thrust + Universal Fissure None
Pandora's Music Box Pandora's Music Box 25 -2% Poisonous Touch Cool Down (-2%) +5% Critical Damage (+5%) +400% All Damage (+200%) Sacred Scroll + Hero's Thrust None
Shock Gauntlets Shock Gauntlets 50 -.5% Boss Life (-.5%) +2% Gold Collection (+2%) +170% All Damage (+85%) Dark Cloak of Life + Future's Fortune None
Vial of Frost Vial of Frost Infinite +5% Chesterson Streak Duration (+5%) +2% Gold Collection (+2%) +70% All Damage (+35%) Ring of Opulance + Future's Fortune None

Tier 5

Almost useless or useless These artifacts have bonuses that are not that useful enough. Other artifacts have better use for W2.

Image Name Max Level Effect 1 (Increase per level) Effect 2 (Increase per level) All Damage (Increase per level) Corrosponding W1 Artifact Notes
Crown of Cleopatra Crown of Cleopatra Infinite +5% Monster Gold (+5%) +5% Poisonous Touch Duration (+5%) +50% All Damage (+25%) Amulet of the Valrunes + Parchment of Importance None
Harp of Medea Harp of Medea 50 -0.5% Boss Life (-0.5%) +5%

Monster Gold

(+5%)

+280% All Damage (+140%) Dark Cloak of Life + Amulet of the Valrunes None
Rod of Great Gales Rod of Great Gales 12 -2% Hero Death Chance (-2%) -10%

Revive

Time

(-10%)

+260% All Damage (+130%) Otherworldly Armor + Warrior's Revival None
Rope of Lashes Rope of Lashes 25 +5% Monster Gold (+5%) +5% Boss Time (+5%) +250% All Damage (+125%) Amulet of the Valrunes + Savior Shield None

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